1. This is a list-in-progress: please send article recommendations and comments to our email at the bottom of the page.

  2. This list aims at collecting studies which combine DYNAMIC (time- or condition-resolved) and MULTIPLEXED - on different molecules - measurements by NMR. Static samples like used in metabolomic or isotopomer analysis are generally outside of the scope of this list.
Title Model type Model components
Protein
 Metabolite
 RNA
 Catalysis
 Unimolecular
 Bimolecular (interactions)
Quantitative reaction model
Nikolaev 2019 Systems NMR: single-sample quantification of RNA, proteins and metabolites for biomolecular network analysis ODE • • • • • •
Semenov 2016 Autocatalytic, bistable, oscillatory networks of biologically relevant organic reactions // (not only NMR data) ODE • •
MRC special issue 2016 Reaction monitoring using NMR (editorial) • •
Thongwichian 2015 A Multiplexed NMR-Reporter Approach to Measure Cellular Kinase and Phosphatase Activities in Real-Time ODE • •
Lerche 2015 NMR insights into the inner workings of living cells (review) • •
Rosenthal 2015 The use of ene adducts to study and engineer enoyl-thioester reductases ODE • •
Meier, 2014 Simultaneous Determination of Binding Constants for Multiple Carbohydrate Hosts in Complex Mixtures analytical • •
Theillet 2013 Site-specific NMR mapping and time-resolved monitoring of serine and threonine phosphorylation in reconstituted kinase reactions and mammalian cell extracts ODE • •
Cordier, 2012 Ordered Phosphorylation Events in Two Independent Cascades of the PTEN C‐tail Revealed by NMR analytical • •
Eicher, 2012 Determining Enzyme Kinetics for Systems Biology with Nuclear Magnetic Resonance Spectroscopy analytical • •
Theillet 2012 Cell signaling, post-translational protein modifications and NMR spectroscopy (review) • •
Balbach 1996 Protein Folding Monitored at Individual Residues During a Two-Dimensional NMR Experiment ODE • •
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Quantitative, but only few reactions
Sekhar, 2018 Conserved conformational selection mechanism of Hsp70 chaperone-substrate interactions analytical • • •
Hoffmann-Thoms 2013 Initiation of Phage Infection by Partial Unfolding and Prolyl Isomerization analytical • • •
Harris, 2013 Hyperpolarized 13C NMR studies of glucose metabolism in living breast cancer cell cultures analytical • •
Maltsev 2013 Site-Specific Interaction between α-Synuclein and Membranes Probed by NMR-Observed Methionine Oxidation Rates ODE • •
Gasmi-Seabrook 2010 Real-time NMR Study of Guanine Nucleotide Exchange and Activation of RhoA by PDZ-RhoGEF ODE • •
W/o reaction model
Limatola 2018 Time-Resolved NMR Analysis of Proteolytic α-Synuclein Processing in vitro and in cellulo • •
Smith, 2014 Integrated RAS Signaling Defined by Parallel NMR Detection of Effectors and Regulators • • • •
Meier, 2014 Hyperpolarized NMR probes for biological assays (review) • •
Xue 2014 New generation NMR bioreactor coupled with high-resolution NMR spectroscopy leads to novel discoveries in Moorella thermoacetica metabolic profiles • •
Rose 2013 Quantitative NMR analysis of Erk activity and inhibition by U0126 in a panel of patient-derived colorectal cancer cell lines • •
Smith 2013 NMR-based functional profiling of RASopathies and oncogenic RAS mutations • • • •
Liokatis 2010 Simultaneous Detection of Protein Phosphorylation and Acetylation by High-Resolution NMR Spectroscopy • •
Marshall 2009 Characterization of the Intrinsic and TSC2-GAP–Regulated GTPase Activity of Rheb by Real-Time NMR • • •
Brecker 2000 Biotransformations monitored in situ by proton nuclear magnetic resonance spectroscopy • •
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== Other papers of interest ==

Title Note
Jimenez-Moreno 2016 Finding the Right Candidate for the Right Position: A Fast NMR-Assisted Combinatorial Method for Optimizing Nucleic Acids Binders multiplexing, small molecules, nucleic acids